Clinical Trials

Life is about looking forward

not back, & one where time is better spent

adding life to years

not years to life

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Science is my passion; I demand scientific rigour and evidence for the claims our products make.

Marcelo Bravo

Marcelo Bravo in his academic dress and mortarboard, on-top of a bicycle.
A mass of silvery liquid.

The science of delivering a superior collagen

The Bioactive Collagen Peptides® we use are a composition of different peptides optimised for specific physiological benefits. The peptides are derived from a highly controlled patented production process of collagen, which is determined by hydrolysation conditions. As a result these Bioactive Collagen Peptides® differ in physiological functionality to other sources of collagen. They are optimised to maximum stimulation of the human cell types involved in collagen biosynthesis.

The scientific evidence

The specific fraction of Bioactive Collagen Peptides® we use in Collagen& has been proven to support our beauty claims in high quality clinical trials. The clinical evidence was obtained in double blind, randomised, placebo controlled clinical studies (RCTs), the gold standard in clinical research and as a result the studies have been published in peer reviewed scientific journals. This is vital because it sets the quality of evidence for Bioactive Collagen Peptides® light years apart from the evidence backing other sources of collagen.

The LIMITLESS potential

Bioactive Collagen Peptides® can stimulate skin metabolism and counteract the loss of collagenous extracellular matrix from the inside. Those who ingest natural Bioactive Collagen Peptides® orally can experience noticeably firmer and smoother skin with fewer wrinkles. The positive effect of Bioactive Collagen Peptides® also shows in an improved skin surface structure, reducing cellulite and a faster nail growth with reportedly less chipping of fingernails.


Several scientific studies investigated the potential of Bioactive Collagen Peptides® with results that found:

Higher skin elasticity 1

Reduction of wrinkles 2

Improved skin surface structure and decrease of cellulite 3

Promoting growth and health of fingernails 4

  1. Proksch et al. (2014). Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study, Skin Pharmacology and Physiology, 27:47-55
  2. Proksch et al. (2014). Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis, Skin Pharmacology Physiology. 27:113-9
  3. Schunck et al. (2015). Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology, Journal of Medicinal Food. 18:1340-1348
  4. Hexsel et al. (2017). Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Journal of Cosmetic Dermatology. 16:520-526

A graph showing the the increased skin elasticity of Colalgen& vs a placebo skin elasticity

Increases skin elasticity

A study with 69 women aged between 35 and 55 years revealed that the specific Bioactive Collagen Peptides® used in Collagen& leads to significantly higher skin elasticity – up to 15% – compared to placebo treatment. This effect could be measured after just 4 weeks of treatment and persisted after 8 weeks of taking.

Significantly reduces wrinkles

Another study with more than 100 women aged between 45 and 65 years shows that in ingesting the specific Bioactive Collagen Peptides® used in Collagen& (2500mg/day) significantly reduces wrinkles after 4 weeks and leads to a significantly higher skin pro-collagen concentration.

A graph showing the large increase in Procollagen accumulation from Collagen& in a treatment.

A graph showing the huge increase to dermal density which Collagen& can give compared to a placebo test.

Significantly decreases cellulite and raises dermal density

A study with 105 women aged between 25 and 50 years shows that the daily oral intake of 2500mg of the specific Bioactive Collagen Peptides® used in Collagen& significantly decreases their cellulite score. The effect was measured after 3 and 6 months supplementation, which also showed the beneficial effect on skins extracellular matrix, restoring the normal structure of the dermis and subcutaneous tissue.